Depression Patient Testimonial

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Depression

What is ketamine infusion therapy for depression?

Ketamine infusion therapy, as a treatment for clinical depression, has been shown to provide rapid relief of symptoms when other treatments have failed. Studies have shown that a series of very low doses of ketamine, infused over one to two hours, has dramatic effects on Post-Traumatic Stress Disorder (PTSD), Anxiety, and Depression including patients suffering from suicidal ideation. The results indicate an almost instant resolution of depression. Some patients can sense relief even after a single infusion. However, for sustained relief, six infusions over a three-week period is needed. Future maintenance infusions may be used to protect against relapse of depression. 


Ketamine infusion therapy can be used to help conditions such as: 


  • Treatment Resistant Depression
  • Major Depressive Disorder 
  • Obsessive Compulsive Disorder (OCD)
  • Suicidal Ideation
  • Anxiety
  • Post-Traumatic Stress Disorder (PTSD)

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Frequently Asked Questions

 

WHAT IS AN INFUSION?

It is a very simple procedure. An IV will be started in your arm or leg and a bag of normal saline mixed with the medication will be slowly given to you.


IS INFUSION THERAPY RIGHT FOR ME?

If you suffer from chronic pain or depression that has not responded to medication or other traditional treatment modalities, then infusion therapy may be an option for you. The procedure is easy to administer and essentially pain free. There will be an free initial consultation with your doctor to see if ketamine infusion therapy is right for you.


WHAT IS KETAMINE?

Ketamine is an FDA-approved anesthetic drug that has been used in hospitals worldwide since the 1960s. In the last few, years numerous articles in medical journals have shown efficacy in using ketamine at subanesthetic doses to treat depression and some chronic pain syndromes. The FDA also approved a form of intranasal ketamine to treat depression in 2019.  Ketamine’s anesthetic effects are mediated by interactions with a member of the glutamate receptor family, the NMDA receptor. It interacts with other receptors as well, including opioid receptors, dopamine receptors, and a receptor known as the AMPA receptor, thought to be an important component of its antidepressant effects.


HOW LONG IS THE INFUSION?

It depends on your diagnosis and protocol. Most of the infusions for depression will be around 2 hours long. After the infusion, you will stay for another 30 minutes to recover. For chronic pain the infusions are usually between 4-6 hours. 


WILL I BE AWAKE?

Yes, the dose that we use will not put you to sleep but, depending on the protocol used for your particular case, you may not recall some or all of the infusion.


WHAT TO EXPECT DURING THE INFUSION?

Some possible side effects include: dizziness, blurred vision, nausea, and dysphoria. These are rare and dose-related. They can be treated immediately to make your experience as pleasant as possible. Shortly after ending the infusion, your mind will be clear. We ask that you do not drive for 24 to 48 hours depending on the protocol received. 


HOW MANY INFUSIONS WILL I NEED?

The response to treatment varies. Most patients require several treatments. The amount of medication and the number of infusions required depends on both the medication and the protocol being used. Some people respond immediately, but most will not feel the true benefit until several treatments have been administered. Generally, for depression, a series of six infusions are needed spaced over a three-week period.


WILL I GET BETTER?

It is possible to undergo ketamine infusion therapy and have no beneficial effect. Patients must make their own decision to voluntarily proceed knowing it may have no beneficial effect. However, the data from many practitioners show that up to 70% of patients will have significant improvement of their symptoms.


CAN I GET ADDICTED?

Studies and clinical experience have found that in the very low doses used, medical setting, lack of access at home, and infrequent dosing, there is virtually no potential for addiction or abuse.


DO I NEED TO STOP MY MEDICATIONS?

We recommend you don’t take Benzodiazepines such as Xanax, Ativan, Valium, or Klonopin. and amphetamine-based stimulants, such as Adderall or Ritalin.


WHAT MEDICAL CONDITIONS WILL EXCLUDE ME FROM KETAMINE TREATMENT?

Uncontrolled high blood pressure or any serious cardiac or respiratory conditions need to be disclosed to avoid complications.


DO I NEED SOMEONE WITH ME?

You will need a responsible adult to take you home. You will not be able to drive for 24 hours after the infusion (some cases 48 hours).


CAN I EAT BEFORE THE INFUSION?

We require that you don’t eat any solid food 8 hours before your infusion. You are allowed to have clear liquids such as water, clear broth, apple juice, or clear tea/coffee (no milk or leaves) up to 2 hours prior to your appointment.

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Northwest Ohio Ketamine Clinic

(419) 344-0563